I understand that I am walking on thin ice by comparing these two cars in this forum, but it is a question that I have. I have owned 2 Accords and both have lasted me a very long time (IS and 330 are durable as well)...but now I am at the time in my life that I can upgrade. Prices are similar...gas mileage is comparable...the IS 350 is quicker to 60 mph but doesn't have a standard transmission as does the 330I...interiors are both nice...I have read a few posts and value the opinions/thoughts provided; let me know what you all think...thanks.